A descriptive study of abdominal complications in patients with mild COVID-19 presenting to the emergency department: a single-center experience in Japan during the omicron variant phase – BMC Gastroenterology – BMC Gastroenterology


Lu H, Stratton CW, Tang YW. Outbreak of pneumonia of unknown etiology in Wuhan, China: the mystery and the miracle. J Med Virol. 2020;92(4):401–2.
Wang C, Horby PW, Hayden FG, Gao GF. A novel coronavirus outbreak of global health concern. Lancet. 2020;395:470–3.
Wu Z, McGoogan JM. Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese center for disease control and prevention. JAMA. 2020;323(13):1239–42.
Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan. China Lancet. 2020;395:497–506.
Yoshimura Y, Sasaki H, Horiuchi H, Miyata N, Tachikawa N. Clinical characteristics of the coronavirus disease 2019 (COVID-19) outbreak on a cruise ship. J Infect Chemother. 2020;26(11):1177–80.
da Rosa Mesquita R, Francelino Silva Junior LC, Santos Santana FM, Farias de Oliveira T, Campos Alcântara R, Monteiro Arnozo G, et al. Clinical manifestations of COVID-19 in the general population: systematic review. Wien Klin Wochenschr. 2021;133:377–82.
Gupta A, Madhavan MV, Sehgal K, Nair N, Mahajan S, Sehrawat TS, et al. Extrapulmonary manifestations of COVID-19. Nat Med. 2020;26:1017–32.
Ye L, Yang Z, Liu J, Liao L, Wang F. Digestive system manifestations and clinical significance of coronavirus disease 2019: a systematic literature review. J Gastroenterol Hepatol. 2020;36(6):1414–22.
Weng LM, Su X, Wang XQ. Pain symptoms in patients with coronavirus disease (COVID-19): a literature review. J Pain Res. 2021;14:147–59.
Elmunzer BJ, Spitzer RL, Foster LD, Merchant AA, Howard EF, Patel VA, et al. Digestive manifestations in patients hospitalized with coronavirus disease 2019. Clin Gastroenterol Hepatol. 2021;19:1355–65.
Suh DC, Kahler KH, Choi IS, Shin H, Kralstein J, Shetzline M. Patients with irritable bowel syndrome or constipation have an increased risk for ischaemic colitis. Aliment Pharmacol Ther. 2007;25(6):681–92.
Longstreth GF, Yao JF. Epidemiology, clinical features, high-risk factors, and outcome of acute large bowel ischemia. Clin Gastroenterol Hepatol. 2009;7(10):1075–80.
Bonaffini PA, Franco PN, Bonanomi A, Giaccherini C, Valle C, Marra P, et al. Ischemic and hemorrhagic abdominal complications in COVID-19 patients: experience from the first Italian wave. Eur J Med Res. 2022;27:165.
Negro A, Villa G, Rolandi S, Lucchini A, Bambi S. Gastrointestinal bleeding in COVID-19 patients. Gastroenterol Nurs. 2022;45(4):267–75.
Krejčová I, Berková A, Kvasnicová L, Vlček P, Veverková L, Penka I, et al. Ischemic colitis in a patient with severe COVID-19 pneumonia. Case Rep Gastroenterol. 2022;16:526–34.
Uhlenhopp DJ, Ramachandran R, Then E, Parvataneni S, Grantham T, Gaduputi V. COVID-19-associated ischemic colitis: a rare manifestation of COVID-19 infection—case report and review. J Investig Med High Impact Case Rep. 2022;10:1–6.
Norsa L, Bonaffini PA, Caldato M, Bonifacio C, Sonzogni A, Indriolo A, et al. Intestinal ischemic manifestations of SARS-CoV-2: results from the ABDOCOVID multicentre study. World J Gastroenterol. 2021;27(32):5448–59.
Funt SA, Cohen SL, Wang JJ, Sanelli PC, Barish MA. Abdominal pelvic CT findings compared between COVID-19 positive and COVID-19 negative patients in the emergency department setting. Abdom Radiol (NY). 2021;46(4):1498–505.
Barkmeier DT, Stein EB, Bojicic K, Otemuyiwa B, Vummidi D, Chughtai A, et al. Abdominal CT in COVID-19 patients: incidence, indications, and findings. Abdom Radiol (NY). 2021;46(3):1256–62.
Stawinski P, Dziadkowiec KN, Marcus A. COVID-19-induced colitis: a novel relationship during troubling times. Cureus. 2021;13(6):e15870.
Kuba K, Imai Y, Rao S, Gao H, Guo F, Guan B, et al. A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury. Nat Med. 2005;11:875–9.
Vaduganathan M, Vardeny O, Michel T, McMurray JJV, Pfeffer MA, Solomon SD. Renin–angiotensin–aldosterone system inhibitors in patients with COVID-19. N Engl J Med. 2020;382:1653–9.
Becker RC. COVID-19-associated vasculitis and vasculopathy. J Thromb Thrombolysis. 2020;50:499–511.
Lukiw WJ, Pogue A, Hill JM. SARS-CoV-2 infectivity and neurological targets in the brain. Cell Mol Neurobiol. 2022;42:217–24.
Tang A, Tong ZD, Wang HL, Dai YX, Li KF, Liu JN, et al. Detection of novel coronavirus by RT-PCR in stool specimen from asymptomatic child, China. Emerg Infect Dis. 2020;26:1337–9.
Xie C, Jiang L, Huang G, Pu H, Gong B, Lin H, et al. Comparison of different samples for 2019 novel coronavirus detection by nucleic acid amplification tests. Int J Infect Dis. 2020;93:264–7.
Xiao F, Tang M, Zheng X, Liu Y, Li X, Shan H. Evidence for gastrointestinal infection of SARS-CoV-2. Gastroenterology. 2020;158:1831-3.e3.
Merad M, Martin JC. Pathological inflammation in patients with COVID-19: a key role for monocytes and macrophages. Nat Rev Immunol. 2020;20:355–62.
Funt SA, Cohen SL, Wang JJ, Sanelli PC, Barish MA. Abdominal pelvic CT findings compared between COVID-19 positive and COVID-19 negative patients in the emergency department setting. Abdom Radiol (NY). 2021;46:1498–505.
Panayiotopoulos YP, Assadourian R, Taylor PR. Aneurysms of the visceral and renal arteries. Ann R Coll Surg Engl. 1996;78:412–9.
Hossain A, Reis ED, Dave SP, Kerstein MD, Hollier LH. Visceral artery aneurysms: experience in a tertiary-care center. Am Surg. 2001;67:432–7.
Katsoularis I, Fonseca-Rodríguez O, Farrington P, Jerndal H, Lundevaller EH, Sund M, et al. Risks of deep vein thrombosis, pulmonary embolism, and bleeding after covid-19: nationwide self-controlled cases series and matched cohort study. BMJ. 2022;377:e069590.
Ano S, Shinkura Y, Kenzaka T, Kusunoki N, Kawasaki S, Nishisaki H. A ruptured left gastric artery aneurysm that neoplasticized during the course of coronavirus disease 2019: a case report. Pathogens. 2022;11(7):815.